Table 1. Risk factors for Candida albicans and non-Candida albicans infections.
| Candida albicans (%) (n = 35) | non-Candida albicans (%) (n = 332) | Statistic | P value | |
|---|---|---|---|---|
| Male | 20 (57.14%) | 211 (63.55%) | 0.747 | 0.455 |
| Age (years)a | 62.00 (45.50, 72.50) | 61.00 (52.00, 71.00) | −0.152 | 0.879 |
| Length of stay (days)a | 33.00 (21.50, 67.00) | 32.00 (23.00, 51.00) | 0.101 | 0.920 |
| Length of stay in ICUa | 3.00 (0.00, 20.50) | 0.00 (0.00, 11.25) | 1.452 | 0.147 |
| Solid tumor | 11 (31.42%) | 173 (52.11%) | 2.327 | 0.020 |
| Diabetes | 4 (11.43%) | 46 (13.86%) | 0.398 | 0.691 |
| Pancreatitisb | 3 (8.57%) | 34 (10.24%) | – | 1 |
| Total parenteral nutrition | 17 (48.57%) | 281 (84.64%) | 5.194 | <0.001 |
| Renal failure | 6 (17.14%) | 31 (9.34%) | – | 0.145 |
| Recent surgery (within 2 weeks) | 11 (31.13%) | 187 (56.33%) | 2.811 | 0.005 |
| Use immunosuppressantsb | 3 (8.57%) | 24 (7.23%) | – | 0.733 |
| ICU | 20 (57.14%) | 149 (44.88%) | 1.384 | 0.166 |
| Hypoproteinemia | 25 (71.43%) | 224 (67.47%) | 0.477 | 0.633 |
| Invasive mechanical ventilation | 17 (48.57%) | 126 (37.95%) | 1.225 | 0.221 |
| Urinary catheter | 22 (62.86%) | 263 (79.22%) | 2.210 | 0.027 |
| Gastric tube | 17 (48.57%) | 196 (59.04%) | 1.193 | 0.233 |
| Central venous catheter | 16 (45.71%) | 213 (64.16%) | 2.142 | 0.032 |
| Drainage catheter | 8 (22.86%) | 237 (71.39%) | 5.797 | <0.001 |
| Endotoxic shockb | 8 (22.86%) | 35 (10.54%) | – | 0.048 |
| Multiple hospitalizations within 2 years (>2 times) | 22 (62.86%) | 202 (60.84%) | 0.232 | 0.816 |
| Persistent fungal infection | 14 (40.00%) | 132 (39.76%) | 0.028 | 0.978 |
| Serum albumin levela (g/l) | 26.20 (21.50, 31.25) | 27.70 (23.90, 31.05) | −1.182 | 0.237 |
| Serum creatinine levela (μmol/L) | 67.00 (49.50, 92.25) | 59.00 (45.00, 79.00) | 1.725 | 0.085 |
| Leukocyte counta (109/l) | 8.84 (6.94, 12.64) | 6.46 (4.39, 9.80) | 3.171 | 0.002 |
| Total bilirubin levela (μmol/l) | 14.30 (8.95, 21.40) | 13.25 (7.65, 24.00) | 0.476 | 0.634 |
| Neutrophil counta (109/l) | 6.75 (4.63, 9.42) | 5.13 (3.47, 8.06) | 2.030 | 0.042 |
| Lymphocyte counta (109/l) | 0.75 (0.56, 1.14) | 0.69 (0.45, 1.00) | 1.375 | 0.169 |
| CRPa (mg/l) | 106.00 (71.53, 166.50) | 86.30 (47.35, 129.50) | 1.520 | 0.128 |
| PCTa (ng/ml) | 1.25 (0.52, 3.05) | 0.50 (0.24, 1.39) | 2.706 | 0.007 |
Note:
a
Described by median and quartile, and the statistic was the Z value; other items were described as numbers (n - %) and the statistic was the χ2 value.
b
Fisher χ2 value.