. Author manuscript; available in PMC: 2022 Jun 18.

Published in final edited form as: Ann N Y Acad Sci. 2020 Oct 16;1480(1):233–245. doi: 10.1111/nyas.14514

Table 1.

Clinical prognosis of corneal thickness, intraocular pressure (IOP), and tear flow after acrolein exposure

	Corneal thickness (μm)				IOP (mmHg)				Tear volume (mm)
Group	Vapor exposure		Topical exposure		Vapor exposure		Topical exposure		Vapor exposure		Topical exposure
	1 min	3 min	1 min	5 min	1 min	3 min	1 min	5 min	1 min	3 min	1 min	5 min

Control	354 ± 8.6	359 ± 6.7	348 ± 6.5	360 ± 5.6	10.0 ± 0.63	10.3 ± 0.88	10.5 ± 0.76	10.7 ± 0.33	13.5 ± 0.76	14.2 ± 0.54	13.3 ± 0.80	13.2 ± 0.95
30 min	504 ± 6.2^***	504 ± 6.4^***	495 ± 7.9^***	495 ± 7.7^**	14.2 ± 0.51^**	16.2 ± 0.75^***	12.7 ± 0.39^ns	11.7 ± 1.07^ns	27.6 ± 0.91^***	32.0 ± 0.88^***	17.3 ± 0.51^ns	17.3 ± 0.70^ns
Day 1	490 ± 13.5^**	501 ± 15.4^***	648 ± 18.9^***	628 ± 16.9^***	22.0 ± 1.46^***	23.7 ± 0.76^***	12.8 ± 0.65^ns	11.3 ± 1.20^ns	26.3 ± 1.88^***	27.7 ± 0.76^***	20.5 ± 1.73^***	20.5 ± 1.84^***
Day 3	497 ± 7.7^***	536 ± 11.1^***	767 ± 19.2^***	843 ± 5.2^***	22.2 ± 0.48^***	22.3 ± 0.92^***	11.0 ± 0.37^ns	11.0 ± 0.82^ns	20.1 ± 0.60^**	23.0 ± 0.97^***	13.5 ± 1.69^ns	10.7 ± 1.26^ns
Day 7	497 ± 3.4^***	543 ± 12.1^***	756 ± 18.3^***	858 ± 11.9^***	13.2 ± 0.54^*	16.2 ± 0.79^***	10.3 ± 0.42^ns	9.8 ± 0.54^ns	12.5 ± 1.84^ns	14.0 ± 1.03^ns	12.7 ± 1.91^ns	8.8 ± 1.11^ns
Day 14	519 ± 5.4^***	559 ± 8.9^***	745 ± 14.5^***	738 ± 14.9^***	11.7 ± 0.92^ns	15.2 ± 1.40^***	10.3 ± 0.67^ns	10.5 ± 0.76^ns	8.3 ± 0.80^*	9.0 ± 1.59^*	9.1 ± 0.61^ns	6.7 ± 0.84^**
Day 21	530 ± 11.1^***	614 ± 15.5^***	721 ± 17.4^***	722 ± 15.9^***	10.2 ± 0.40^ns	11.7 ± 0.56^ns	10.8 ± 0.70^ns	10.0 ± 0.58^ns	11.0 ± 1.15^ns	9.5 ± 1.09^ns	6.5 ± 0.76^**	7.8 ± 0.95^*
Day 28	513 ± 7.3^***	628 ± 16.8^***	692 ± 15.9^***	716 ± 15.6^***	11.2 ± 0.40^ns	12.5 ± 0.50^ns	10.5 ± 0.56^ns	10.2 ± 0.48^ns	10.5 ± 1.09^ns	8.7 ± 1.31^*	7.2 ± 0.70^**	6.5 ± 1.06^**

*P < 0.05; **P < 0.01; ***P < 0.001.

^ns,

not significant.