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. 2022 Jun 14;15:3477–3499. doi: 10.2147/JIR.S357144

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© 2022 Wang et al.

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Effects of SORBS1 knockdown or overexpression on BC cells’ invasion and migration. (A) Quantitative PCR analysis of SORBS1 expression levels in si-SORBS1 control, si-SORBS1, oe-SORBS1 control and oe-SORBS1 breast cancer cell lines (MCF-7 and MDA-MB-231). (B) Western blot of SORBS1 expression levels in si-SORBS1 control, si-SORBS1, oe-SORBS1 control and oe-SORBS1 breast cancer cell lines (MCF-7 and MDA-MB-231). (C) Effects of SORBS1 knockdown or overexpressed on invasion of MDA-MB-231 breast cancer cells. (D) Effects of SORBS1 knockdown or overexpressed on invasion of MCF-7 breast cancer cells. (E) Effects of SORBS1 knockdown or overexpressed on migration of MDA-MB-231 breast cancer cells showed by scratch assays. (F) Effects of SORBS1 knockdown or overexpressed on migration of MCF-7 breast cancer cells showed by scratch assays. **:P < 0.01; ***:P < 0.001.