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Imaging of 124I avidity in Patient 4 at baseline and after combination vemurafenib plus CDX-3379. Baseline imaging of Patient 4 from the first 124I PET-CT lesional dosimetry showed no avidity in either the (A) thyroid bed, metastatic lymph node, or (B) lung metastases. Imaging from the second 124I PET-CT lesional dosimetry showed increased avidity after vemurafenib plus CDX-3379 in both the (C) thyroid bed, metastatic lymph node, and (D) lung metastases.
