TABLE 6.
Summary of findings table.
| Certainty assessment |
No. of patients |
Effect |
Certainty | Importance | ||||||||
| No. of studies | Study design | Risk of bias | Inconsistency | Indirectness | Imprecision | Other considerations | Exercise training | Non-exercise | Relative (95% CI) | Absolute (95% CI) | ||
| Fatigue (assessed with: questionnaire) | ||||||||||||
| 21 | Randomized trials | Not serious | Seriousa | Not serious | Not serious | None | 550 | 566 | - | SMCD 0.374 SD lower (0.521 lower to 0.227 lower) | ⊕⊕⊕○ Moderate |
IMPORTANT |
| Energy (assessed with: questionnaire) | ||||||||||||
| 21 | Randomized trials | Not serious | Seriousa | Not serious | Not serious | None | 636 | 590 | - | SMCD 0.415 SD higher (0.252 higher to 0.422 higher) | ⊕⊕⊕○ Moderate |
IMPORTANT |
| Vitality (assessed with: questionnaire) | ||||||||||||
| 21 | Randomized trials | Not serious | Seriousa | Not serious | Not serious | None | 2,677 | 2,031 | - | SMCD 0.537 SD higher (0.404 higher to 0.671 higher) | ⊕⊕⊕○ Moderate |
IMPORTANT |
aLarge and significant heterogeneity, all effects are not in the same direction.