Table 2:

Progression of MGUS to MM and LP for those with autoimmune disease compared to those without by subgroups

	Hazard ratio✣	95% CI✣✣	p value
Progression to LP✣✣✣
Overall	0.84	0.75–0.94	0.0016
Autoantibody not detected	0.81	0.70–0.94	0.0043
Organ involvement	0.88	0.76–1.01	0.0742
Systemic involvement	0.79	0.64–0.96	0.0209
Diagnosis made after 1993	0.87	0.77–0.98	0.0161
Women	0.90	0.78–1.05	0.1832
Men	0.78	0.66–0.91	0.0016
Progression to MM✣✣✣✣
Overall	0.83	0.73–0.94	0.0036
Autoantibody not detected	0.77	0.64–0.91	0.0030
Organ involvement	0.87	0.74–1.03	0.1153
Systemic involvement	0.79	0.62–0.996	0.0463
Diagnosis made after 1993	0.85	0.74–0.98	0.0234
Women	0.81	0.68–0.97	0.0197
Men	0.84	0.70–1.02	0.0746

^✣Adjusted for age, gender and year of diagnosis

^✣✣CI denotes confidence interval

^✣✣✣Lymphoproliferative disease

^✣✣✣✣Multiple myeloma