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. Author manuscript; available in PMC: 2022 Jun 19.
Published in final edited form as: Eur J Haematol. 2020 Dec 28;106(3):380–388. doi: 10.1111/ejh.13563

Table 4:

Progression for those with autoimmune disease compared to those without by age, M-protein concentration and immunoglobulin type

Hazard ratio✣ 95% CI✣✣ p value
Progression to LP✣✣✣
 M-protein ≥1,5 g/dL 0.66 0.38–1.13 0.1282
 M-protein <1,5 g/dL 0.94 0.65–1.37 0.7491
 IgG M-protein 0.75 0.52–1.08 0.1238
 IgA M-protein 0.51 0.26–1.00 0.0506
 IgM M-protein 0.91 0.44–1.88 0.7918
 Biclonal M-protein 1.09 0.43–2.74 0.8579
Progression to MM✣✣✣✣
 M-protein ≥1,5 g/dL 0.80 0.45–1.44 0.4629
 M-protein <1,5 g/dL 0.44 0.22–0.86 0.0160
 IgG M-protein 0.60 0.39–0.92 0.0204
 IgA M-protein 0.39 0.17–0.88 0.0229
 IgM M-protein 7.11 0.57–88.10 0.1268
 Biclonal M-protein 1.15×10−8 0−∞ 9.98×10−1
✣

Adjusted for age, gender and year of diagnosis

✣✣

CI denotes confidence interval

✣✣✣

Lymphoproliferative disease

✣✣✣✣

Multiple myeloma