Table 5.
Comparison between sustained virological response (SVR) and response-relapse (RR) in HCV patients with IL-10 genotypes
| Genotype | SVR (n = 98) | RR (n = 30) | OR (95% CI) | P value | Allele frequency | ||
|---|---|---|---|---|---|---|---|
| SVR | RR | ||||||
| IL-10 | AA | 47 (48%) | 10 (33·5%) | 1 (Ref.) | 0·71 | 0·55 | |
| −1082A/G | AG | 46 (47%) | 13 (43·5%) | 1·3 (0·53–3·33) | 0·54 | ||
| (MnII) | GG | 5 (5%) | 7 (23%) | 6·6 (1·73–25·01) | 0·00* | 0·29 | 0·45 |
| IL-10 | CC | 36 (37%) | 8 (27%) | 1 (Ref.) | 0·62 | 0·53 | |
| −819C/T | CT | 50 (51%) | 16 (53%) | 1·4 (0·55–3·72) | 0·45 | ||
| (MaeIII) | TT | 12 (12%) | 6 (20%) | 2·2 (0·65–7·80) | 0·19 | 0·38 | 0·47 |
| IL-10 | AA | 24 (24·5%) | 2 (6·5%) | 1 (Ref.) | 0·37 | 0·2 | |
| −592A/C | AC | 26 (26·5%) | 8 (26·5%) | 3·7 (0·71–19·14) | 0·10 | ||
| (RsaI) | CC | 48 (49%) | 20 (67%) | 5·0 (1·07–23·18) | 0·02* | 0·63 | 0·8 |
Ref., reference category; OR, odds ratio; CI, confidence interval.
*
P < 0·05 is considered statistically significant.