Table 7.
Comparison between sustained virological response (SVR) and non-SVR in HCV patients with IL-10 genotypes
| Genotype | SVR (n = 98) | Non-SVR (n = 52) | OR (95% CI) | P value | Allele frequency | ||
|---|---|---|---|---|---|---|---|
| SVR | Non-SVR | ||||||
| IL-10 | AA | 47 (48%) | 17 (33%) | 1 (Ref.) | 0·71 | 0·53 | |
| −1082A/G | AG | 46 (47%) | 21 (40%) | 1·26 (0·59–2·69) | 0·54 | ||
| (MnII) | GG | 5 (5%) | 14 (27%) | 7·7 (2·42–24·74) | 0·00* | 0·29 | 0·47 |
| IL-10 | CC | 36 (37%) | 12 (23%) | 1 (Ref.) | 0·62 | 0·51 | |
| −819C/T | CT | 50 (51%) | 29 (56%) | 1·7 (0·78–3·86) | 0·17 | ||
| (MaeIII) | TT | 12 (12%) | 11 (21%) | 2·7 (0·96–7·83) | 0·06 | 0·38 | 0·49 |
| IL-10 | AA | 24 (24·5%) | 4 (8%) | 1 (Ref.) | 0·37 | 0·17 | |
| −592A/C | AC | 26 (26·5%) | 10 (19%) | 2·3 (0·64–8·34) | 0·2 | ||
| (RsaI) | CC | 48 (49%) | 38 (73%) | 4·7 (1·51–14·86) | 0·00* | 0·63 | 0·83 |
Ref., reference category; OR, odds ratio; CI, confidence interval.
*
P < 0·05 is considered statistically significant.