Fig. 8.

Effects of the secretome from IFN-γ- or IL-4-induced microglia on PI3K/Akt signaling pathway during NSPCs proliferation or differentiation. A–D Western blotting showing the levels of PI3K, Akt, and phospho-Akt (p-Akt) in NSPCs under different treatment conditions. Levels of PI3K and Akt were normalized to those of β-actin, and levels of p-Akt was normalized to those of Akt. Data are showed Mean ± SEM, n = 4–6, *P < 0.05, **P < 0.01, ***P < 0.001 vs PBS group, ^#P < 0.05, ^##P < 0.01, ^###P < 0.001 vs IL-4 group