Figure 4.

Silencing of WTAP reduces the migration and invasive capacity of OC cells in vitro and metastasis in vivo. (a and b) Representative migration and invasion images of WTAP silenced and Nc cells in A2780 and 3AO. Original magnification: 200x. Calculations of cell number were performed with three randomly selected fields. (c and d) Representative wound healing images of A2780 and 3AO at 0 and 24 h, respectively, the cell boundary was marked by the dotted black line. ^∗P < 0.05, ^∗∗P < 0.01. (e) Pulmonary metastasis models were established and typical diagram was shown. (f) Statistical analysis of numbers of pulmonary metastatic nodules.