Table 2.
Top 5 results of enrichment analysis of BP, CC, MF, and the pathways of SQP.
| Ontology | ID | Description | GeneRatio | BgRatio | p value | p.adjust | q value |
|---|---|---|---|---|---|---|---|
| BP | GO: 0032496 | Response to lipopolysaccharide | 6/8 | 330/18670 | 7.92e-10 | 6.31e-07 | 1.47e-07 |
| BP | GO: 0002237 | Response to molecule of bacterial origin | 6/8 | 343/18670 | 9.99e-10 | 6.31e-07 | 1.47e-07 |
| BP | GO: 0150076 | Neuroinflammatory response | 4/8 | 75/18670 | 1.66e-08 | 6.99e-06 | 1.63e-06 |
| BP | GO: 0010575 | Positive regulation of vascular endothelial growth factor production | 3/8 | 29/18670 | 1.88e-07 | 5.54e-05 | 1.29e-05 |
| BP | GO: 0002675 | Positive regulation of acute inflammatory response | 3/8 | 31/18670 | 2.31e-07 | 5.54e-05 | 1.29e-05 |
| MF | GO: 0005125 | Cytokine activity | 3/8 | 220/17697 | 1.01e-04 | 0.006 | 0.002 |
| MF | GO: 0005126 | Cytokine receptor binding | 3/8 | 286/17697 | 2.20e-04 | 0.006 | 0.003 |
| MF | GO: 0033613 | Activating transcription factor binding | 2/8 | 85/17697 | 6.27e-04 | 0.012 | 0.005 |
| MF | GO: 0048018 | Receptor ligand activity | 3/8 | 482/17697 | 0.001 | 0.015 | 0.006 |
| MF | GO: 0070851 | Growth factor receptor binding | 2/8 | 134/17697 | 0.002 | 0.018 | 0.007 |
| KEGG | hsa04657 | IL-17 signaling pathway | 5/8 | 94/8076 | 1.05e-08 | 4.75e-07 | 1.87e-07 |
| KEGG | hsa05163 | Human cytomegalovirus infection | 6/8 | 225/8076 | 1.17e-08 | 4.75e-07 | 1.87e-07 |
| KEGG | hsa04933 | AGE-RAGE signaling pathway in diabetic complications | 5/8 | 100/8076 | 1.43e-08 | 4.75e-07 | 1.87e-07 |
| KEGG | hsa05142 | Chagas disease | 5/8 | 102/8076 | 1.58e-08 | 4.75e-07 | 1.87e-07 |
| KEGG | hsa04668 | TNF signaling pathway | 5/8 | 112/8076 | 2.54e-08 | 6.10e-07 | 2.41e-07 |