Table 3.
Factors Associated with CPAP Titration Success During the Therapeutic Night. CPAP Acceptance Using Univariable and Multivariable Logistic Regression Analyses
| Variables in the Equation | p-value | OR [95% C.I.] | |
|---|---|---|---|
| Univariable Model | |||
| Age (Year) | 0.24 | 1.04 [0.97–1.12] | |
| Body mass index (kg/m2) | 0.012 | 1.334 [1.07–1.67] | |
| PaCO2 (mmHg) | 0.25 | 1.21 [0.87–1.68] | |
| HCO3 (mmol/L) | 0.14 | 1.39 [0.90–2.15] | |
| FVC (% predicted) | 0.99 | 1.00 [0.95–1.05] | |
| FEV1 (% predicted) | 0.91 | 0.99 [0.95–1.047] | |
| Apnea hypopnea index (events/hr) | 0.049 | 1.14 [1.001–1.30] | |
| Desaturation index (desaturations/hr) | 0.034 | 1.22 [1.02–1.46] | |
| Time with SpO2 <90% (mins) | 0.24 | 1.754 [0.69–4.43] | |
| Lowest recorded SpO2 (%) | 0.05 | 0.74 [0.55–1.003] | |
| Mean nocturnal SpO2 (%) | 0.10 | 0.71 [0.474–1.07] | |
| Sex (Female) | 0.23 | 3 [0.50–17.95] | |
| Diabetes mellitus | 0.54 | 1.667 [0.32–8.59] | |
| Hypertension | 0.08 | 4.72 [0.86–26.04] | |
| Multivariable logistic model (Forward Wald method)* | |||
| Desaturation index (desaturations/hr) | 0.027 | 1.33 [1.033–1.712] | |
Notes: *Multicollinearity: none. Overall accuracy: 80.6%, Sensitivity: 91.7%, Specificity: 42.9%, Area under the curve (ROC): 87.2%, Omnibus tests of model: p=0.002, Hosmer-Lemeshow goodness of fit: p=0.609, Nagelkerke R square: 42.2%.