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The circ_0004951/miR-93-5p/ NLRP3 axis regulates HG-induced pyroptosis in HK2. LDH release in each group (A). Caspase-1 activity in each group (B). ELISA results showing expression levels of IL-1β and IL-18 in each group (C,D). HG, high glucose; HK2, human renal tubular epithelial cell line; LDH, lactate dehydrogenase. Values are expressed as mean ± SD. *p < 0.05 vs. control.
