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A timeline of selected studies of closed-loop systems. CLS = closed-loop system; HCLS = hybrid closed-loop system. References: Weinzimer et al., (24), Phillip et al., (42), Russell et al., (43), Thabit et al., (26), Bergenstal et al., (27), Stewart et al., (44), Kovatchev et al., (45), El-Khatib et al., (46), Brown et al., (47), Tauschmann et al., (48), Lal et al., (32).
