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. 2022 Apr 6;113(6):2085–2096. doi: 10.1111/cas.15344

TABLE 4.

Bleeding adverse events

Grade

Cohort A

Treatment‐naïve (N = 18)

Cohort B

Relapsed/refractory (N = 9)

All (N = 27)
1 2 3–5 1 2 3–5 1 2 3–5
Any 5 (28) 0 0 3 (33) 1 (11) 0 8 (30) 1 (4) 0
Purpura 1 (6) 0 0 2 (22) 0 0 3 (11) 0 0
Epistaxis 1 (6) 0 0 1 (11) 0 0 2 (7) 0 0
Contusion 0 0 0 2 (22) 0 0 2 (7) 0 0
Traumatic hematoma 0 0 0 0 1 (11) 0 0 1 (4) 0
Anal hemorrhage 1 (6) 0 0 0 0 0 1 (4) 0 0
Hematoma 1 (6) 0 0 0 0 0 1 (4) 0 0
Mouth hemorrhage 1 (6) 0 0 0 0 0 1 (4) 0 0
Petechiae 1 (6) 0 0 0 0 0 1 (4) 0 0
Conjunctival hemorrhage 0 0 0 1 (11) 0 0 1 (4) 0 0
Hemorrhage subcutaneous 0 0 0 1 (11) 0 0 1 (4) 0 0

Number (%) of patients is shown.