FIGURE 2.

Cytotoxic effect of neutrophils from blood and tumor tissue. (A–C) Viability of luciferase‐tagged tumor cells after 24 h of coculture with isolated neutrophils from blood and tumor tissues (three types). n = 5 (D) Glutamate release from three tumor cell lines after treating with gradient riluzole for 24 h. *Means compared to control. (E, F) Glutamate concentration in tumor tissues and serum from tumor‐free mice (control), LLC and riluzole‐treated LLC‐bearing mice. *Means compared to LLC. (G) Intratumoral neutrophil cytotoxic effects on LLC at different coculture ratios. */**Differences between riluzole group and blank group. n = 5. Data are presented as mean ± SEM