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. 2022 Jun 6;13:874211. doi: 10.3389/fneur.2022.874211

Table 2.

Characteristics of people with MS according to anti-PAD2 antibody status.

Anti-PAD2+ Anti-PAD2– p-Value
(n = 17) (n = 71)
Age (years), mean ±SD 50.8 ± 14.6 48.3 ± 12.0 0.47
Male, n (%) 4 (23.5%) 21 (29.6%) 0.78
White, n (%) 14 (82.4%) 51 (71.8%) 0.54
Duration of illness*(years), mean ±SD 16.6 ± 14.9 11.7 ± 9.1 0.10
Treatment*
 Avonex, n (%) 2 (11.8%) 3 (4.2%) 0.25
 Betaseron, n (%) 0 (0%) 1 (1.4%) 1.0
 Rebif, n (%) 3 (17.6%) 7 (9.9%) 0.40
 Copaxone, n (%) 6 (35.3%) 20 (28.2%) 0.57
 Gilenya, n (%) 0 (0%) 1 (1.4%) 1.0
 Lemtrada, n (%) 0 (0%) 1 (1.4%) 1.0
 Tecfidera, n (%) 3 (17.6%) 6 (8.5%) 0.37
 Rituximab, n (%) 0 (0%) 3 (4.2%) 1.0
 Tysabri, n (%) 2 (11.8%) 12 (16.9%) 1.0

Anti-PAD2+, anti-PAD2 antibody positive; Anti-PAD2–, anti-PAD2 antibody negative.

*Duration of illness data was available for n = 87 and treatment data was available for n = 70 people.