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. 2022 Jun 6;13:853113. doi: 10.3389/fgene.2022.853113

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Copyright © 2022 Lu, Xu, Wang, Zhao, Peng, Wang and Zhang.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Identification of mutation signature in different subtypes. (A,B) Comparison of TMB and MSI in ESCC patients with different immune subtypes. (C) Top 30 mutated genes in the IS1 and IS2 subtypes.