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. 2020 Aug 19;100(15):5861. doi: 10.2340/00015555-3612

Fig. 1.

Fig. 1

Histopathological findings in mini-chilblain-like pattern. (Haematoxylin & Eosin (H&E), A: 4x, B: 20x) COVID-19-positive 22-year-old patient. Presenting clinically with urticarial lesions at an early stage (biopsy 2 days after dermatosis onset). Diffuse oedema of the dermis, mild lymphocytic perivascular and interstitial infiltration were observed (arrows). Swollen superficial dermal vessels with eosinophils (arrow). (H&E, C: 4x, F: 20x) Patient at high risk of COVID-19, PCR swab-negative, 10 years of age. Under lockdown at home with COVID-19-positive mother. Presenting clinically with pityriasis lichenoides like lesions. Histology showed a dense periductal lymphocytic cuff. Dense perivascular and periductal lymphocytic cuff. (H&E, D: 4x) Patient at high risk of COVID-19, PCR swab-negative, 34 years of age. Under lockdown at home with COVID-19-positive wife. Presenting clinically with urticarial target-like lesions. Dense perivascular and periductal lymphocytic cuff (arrows). Inset: abnormally dilated and engorged large vessel. Swollen lymphatic-like vessel and periductal lymphocytic cuff. (H&E, E: 4x) COVID-19-positive patient, 45 years old. Presenting clinically with target-like lesions and chilblain-like ulcerated plaque. (F, same patient as in Fig. C. H&E, 10x). Dense perivascular and periductal lymphocytic cuff (arrows). Inset: Cuticular positivity of the eccrine gland using the SARS-CoV-2 (2019-nCoV) nucleocapsid antibody.