TABLE I.
Study | Number of patients | Method of assessment for malignancy | Sensitivity for malignancy | Specifcity for malignancy | Accuracy for malignancy | % malignant lesion | Mean SUVmax Benign | Mean SUVmax malignant |
---|---|---|---|---|---|---|---|---|
[32] | 93 | SUVmax >3.2 | 95.2% | 81.3% | 88% | 35.9% | 2.4 | 8.4 |
Adr SUVmax/Liver SUVmax > 1.6 | 92.9% | 86.7% | 79.6% | |||||
SUVmax>2.8 and <10% of pixels <0 HU | 100% | 97.3% | 95.7% | |||||
[31] | 81 | SUVmax ≥ 4.2 | 88.6% | 88.2% | 88.5% | 67.3% | 3.0 | 8.8 |
Adr SUVmax/Liver SUVavg > 1.68 | 90% | 91.1% | 90.4% | |||||
[35] | 105 | Visual ≥ liver | 94% | 83% | 90% | 61% | 2.4 | 6.0–8.4 |
[37] | 109 | Visual >> Liver | 97% | 94% | 45% | 2.29 | 12.2 | |
Adr SUVmax/Liver SUVmax >1 | 100% | 100% | ||||||
[109] | 96 | Adr SUVavg/Liver SUVavg ≥1 | 83.3% | 85.4% | 85% | 26.8% | 1.9 a | 7.2 a |
[36] b | 59 | Visual>liver | 75% | 89% | 86.4% | 20% | 4.2 | 9.2 |
Adr SUVmax/Liver SUVavg ≥ 1.0 | 100% | 95.7% | 96.6% | |||||
[34] | 74 | Visual > Liver | 93% | 96% | 95% | 37.5% | 2.6 | 5.5 |
SUVmax > 3.4 | 95% | 86% | ||||||
[29] | 150 | SUVmax>3.1 | 98.5% | 92% | 39% | 1.78 | 10.13 | |
SUVmax >3.1 or >10 HU | 100% | 98% | ||||||
[30] | 147c | SUVmax>3.1 | 97.3% | 75.9% | 84.2% | 39% | 3.0 | 10.4 |
Adr SUVmax/Liver SUVavg >1 | 97.3% | 65.5% | 77.9% |
Adr, adrenal; Liv, liver.
Mean SUVavg values.
Recalculated from data provided in article.
Lung cancer only.