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. 2022 Jun 6;10:913839. doi: 10.3389/fbioe.2022.913839

TABLE 3.

Antimicrobial peptide derived from oyster whole Tissue.

Species Name of AMP Enzyme used Oyster peptides and/or MW Results References
Crassostrea gigas Thermolysin LLEYSI, LLEYSL Inhibit the HIV-1 protease Lee & Maruyama (1998)
Crassostrea virginica Plasma peptides (<10 kDa) Against the Gram-positive bacteria (B. megaterium) Anderson and Beaven (2001)
Crassostrea gigas SPE Cytotoxic activity against vero cells Olicard et al. (2005)
Crassostrea gigas Cg-Defh1 and Cg-Defh2 GFGCPRDQYKCNSHCQSIGCRAGYCDAVTLWLRCTCTDCNGKK and GFGCPGDQYECNRHCRSIGCRAGYCDAVTLWLRCTCTGCSGKK Recombinant AMP’s based on prokaryotic expression of Escherichia coli Gonzalez et al. (2007)
Crassostrea gigas CgPep33 Alcalase Antifungul activity against Botrytis cinerea Liu et al. (2007)
Crassostrea gigas CgPep33 Alcalase Antibacterial activity against Gram-positive bacteria (Bacillus subtilis, Streptococcus aureus) and Gram-negative bacteria (Escherichia coli, Pseudomonas aeruginosa), fungi (B. cinerea, Penicillium expansum) Liu et al. (2008)
Crassostrea gigas Cg-Prp Alcalase ILENLLARSTNEDREGSIFDTGPIRRPKPRPRPRPEG Against Gram-positive bacteria (Micrococcus lysodeikticus, Brevibacterium stationis, Microbacterium maritypicum), Gram-negative bacteria (E. coli SBS363, Enterobacter cloacae, Erwinia carotovora, Klebsiella pneumonia), fungi (Fusarium oxysporum, Botrytis cinerea) Gueguen et al. (2009)
Crassostrea gigas Cg-BigDef1 QAQALLPIASYAGLTVSAPVFAALVTVYGAYALYRYNIRRRENSYQRIRSDHDSHSCANNRGWCRPTCFSHEYTDWFNNDVCGSYRCCRPGRSG (10.7 kDa) Against gram positive and negative bacteria Rosa et al. (2011)
  Cg-BigDef1 QAQALLPIASYAGLAVSPPVFAALVTAYGVYALYRYNIRRENSDHDSHSCANNRGWCRPTCYSYEYTDWFNNDVCGSYRCCRPGRRG
  Cg-BigDef1 QAQILLPIASYAGLTVTAPVFAALVAAYGIYAVTRYAIRKRRIVMYSDSHSCANNRGWCRESCFSHEYTDWANTFGVCGSYFCCRPY
Crassostrea gigas cgTβ Trypsin (4656.4 Da) Against Gram-positive bacteria (B. subtilis KCTC Nam et al. (2015)
1021) and Gram-negative bacteria (E. coli D31)
Crassostrea gigas Alcalase, bromelin, neutrase (6500 Da) Against Gram-positive bacteria (Listeria monocytogenes, Staphylococcus aureus) and Gram-negative bacteria (E. coli, Pseudomonas aeruginosa, Vibriyo parahaemolytius, V. harveyi) Zhang et al. (2015)