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. 2022 Jun 6;10:913839. doi: 10.3389/fbioe.2022.913839

TABLE 5.

Bioactive peptides derived from oyster gill tissue and mantle tissue.

Biological activity Species Enzyme used Oyster peptides and/or MW Results References
Anti-microbial Crassostrea virginica (Gill tissue) GFGCPWNRYQCHSHCRSIGRLGGYCAGSLRLTCTCYRS (4265.0 Da) Against Gram-positive bacteria (Lactococcus lactis subsp. lactis, S. aureus) and Gram-negative Seo et al. (2005)
bacteria (E. coli D31, Vibriyo parahemolyticus)
  Crassostrea gigas Trypsin cgUbiquitin (8471 Da) Against Gram-positive bacteria (Streptococcus iniae), Gram-negative bacteria (V. parahemolyticus) Seo et al. (2013a)
(Gill tissue)
    cgMolluscidin, AATAKKGAKKADAPAKPKKATKPKSPKKAA Against Gram-positive bacteria (B. subtilis, Seo et al. (2013b)
KKAGAKKGVKRAGKKGAKKTTKAKK (5.5 kDa) Micrococcus luteus, S. aureus) and Gram-negative bacteria (E. coli, Salmonella enterica,V. parahaemolyticus)
    AKSKNHTSHNQNRKQHRNGIHRPKTYRYPSMKGVDPKFL KNLKFSKKHNKNTKK(6484.6 Da) Against Gram-positive bacteria (Bacillus subtilis Seo et al. (2017)
KCTC 1021) and Gram-negative bacteria
(Escherichia coli D31, Vibrio parahaemolyticus)
  Crassostrea gigas Cg-Defm, GFGCPGNQLKCNNHCKSISCRAGYCDAATLWL Against Gram-positive bacteria (M. lysodeikticus, Gueguen et al. (2006)
(Mantle tissue) RCTCTDCNGKK S. aureus, S. hemeolyticus, B. megaterium,
B. stationis, M. maritypicum)
Osteogenic Pinctada fucata (Mantle tissue) PFMG4 Homology with C1q protein in different species, mainly in MC3T3-E1 osteoblast cell Wang et al. (2015)