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. 2022 Feb 10;16(12):2367–2383. doi: 10.1002/1878-0261.13182

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© 2022 The Authors. Molecular Oncology published by John Wiley & Sons Ltd on behalf of Federation of European Biochemical Societies.

This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.

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Fig. 4 — CircRNA expression in early‐stage NSCLC samples. (A) Venn diagram displaying circRNAs identified in early‐ and late‐stage samples, featuring those shared by both cohorts. DE circRNAs are indicated. (B) Differential expression analysis of log2‐normalized counts between the early‐stage lung cancer cohort (n = 27) and control (n = 16) FFPE tissues. circEPB41L2, circSOX13, and circBNC2 were found downregulated and circFUT8, circCHD9, and circ_C1orf116 were found upregulated as previously described with all stages of lung cancer.