Fig. 5.

iPSC transplantation promoted morphological and functional recovery after SCI. A HE staining of spinal cord tissue at 14 d after injury, scale bar = 200 µm (top) or 110 µm (lower). B LFB staining was performed to identify demyelination at 14 d, scale bar = 200 µm or 110 µm. C, D Nissl staining to assess the loss of Nissl bodies at 14 d, and statistical graph showing numbers of Nissl bodies in each group (**p < 0.01, ***p < 0.001 vs. SCI group, ^#p < 0.05 GFP vs. H-Apln group, mean ± SD). E Neurological function assessed by BBB score from 0 to 14 d after SCI (*p < 0.05, **p < 0.01 SCI vs. GFP group; ^##p < 0.01, ^###p < 0.001 SCI vs. H-Apln group, ^&&&p < 0.001 GFP vs. H-Apln group, mean ± SD)