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. 2022 Jun 20;24:42. doi: 10.1186/s13058-022-01535-x

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© The Author(s) 2022

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

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Fig. 3 — Weight Maintenance after OVX alters plasma proteins associated with tumor progression and metabolism in lean and obese rats. A GO Biological Processes common to plasma cytokines that were higher (p < 0.1) in WM versus AdLib lean and obese rats at the end of study. B–D Examples of cytokines that were greater in plasma from WM versus AdLib rats, including IL-2 (B), MIP2/CXCL2 (C), and MIP-1α /CCL3 (D). E GO Biological Processes common to plasma cytokines that were lower (p < 0.1) in WM versus AdLib lean and obese rats at the end of study. F–H Examples of cytokines or growth factors that were lower in plasma from WM versus AdLib rats, including BDNF (F), TNFα (G), and FGF2 (H)