Skip to main content
. Author manuscript; available in PMC: 2023 Jan 1.
Published in final edited form as: Mutat Res Rev Mutat Res. 2021 Dec 20;789:108409. doi: 10.1016/j.mrrev.2021.108409

Fig. 3. Schematic representation of the uptake and nitrosation of nicotine in E-cig aerosols, the metabolism, subsequent degradation, the induction of DNA damage that follows, and the inhibition of DNA repair.

Fig. 3.

This scheme is based on the results from the DNA adduct analysis, DNA repair analysis, and tumorigenesis in lung and bladder tissues of mice exposed to ECAs (61, 105, 206). Symbols are the same as in Fig. 2.