Table 2.

A summary of the quantification of γ-OH-PdG,α-methyl-γ-OH-PdG, O⁶-medG and BPDE-dG adduct formed in the lungs, heart, liver and bladder of mice exposed to MTS¹, SSS² and E CA³.

Aerosol	Exposure	Nicotine In the chamber (μg/m3)	Source of Aerosol	Aerosol Level (mg/m3)	Organ	Exposed (n=10)/unexposed (n=10)
						γ-OH-PdG/105 dG	α-methyl-γ −OH-PdG/105 dG	O6-me-dG/107 dG	BPDE-dG/107 dG
MTS1	3 cig4 6 h/d 5 d/wk 12 wks	871.5	2R4F cig 2 puffs/min 35 ml/puff	75	Lung	0.55/0.05****	0.19/ND	0.05/0.25 ns	0.75/0.75 ns
					Heart	0.15/0.15 ns	-----	0.3/0.4 ns	0.4/0.4 ns
					Liver	0.4/0.3 ns	-----	0.075/0.07 5 ns	0.6/0.6 ns
					Bladder	0.3/0.05***	ND/ND	0.2/0.1 ns	0.2/0.1 ns
SSS2	3 cig4 6 h/d 5 d/wk 16 wks	36	2R4F cig 2 puffs/min 35 ml/puff	0.454	Lung	0.5/0.3*	ND		2/2 ns
					Heart	0.05/0.05 ns	-----		2/2 ns
					Liver	0.4/0.35 ns	-----		2/1.75 ns
					Bladder	0.7/0.4**	ND		1.8/1.7 ns
ECA3	E-liquid (Nicotine 10 mg/ml +PG and VG) 3 h/d 5 d/wk 12 wks	129	E-juice (nicotine, PG and VG) puffs/min 35 ml/puff	130	Lung	1/0.2***	ND	4/0.2****	-----
					Heart	0.3/0.05****	-----	0.5/0.1***	-----
					Liver	0.04/0.035 ns	-----	1/1 ns	----
					Bladder	0.4/0.05***	ND	1.25/0.2**	----

¹Results from Weng et al (20).

²Results from Lee et al., (19).

⁴3 cig: smoke generated from 3 cigarettes burning at the same time.

³results from Lee et al., (61).

ND: not detectable; _____: not detected.

P value:

^*p<0.05,

^**p<0.01,

^***p<0.001,

^****p,0.0001, ns= not significant.