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. 2022 Jun 16;16:1865–1883. doi: 10.2147/DDDT.S214174

Table 2.

Meta-Analysis Results on Motor Function in Patients with SMA Types 2 and 3 Treated with Nusinersen

Instrument Pooled Mean 95% CI P
HFMSE Overall 2.27 1.41–3.13
Untreated −1.00 −1.33–0.67
3.27 <0.0001
RULM Overall 1.11 0.53–1.69
Untreated 0.47 −0.79–1.74
=0.370
6MWT Overall 19.80 m 6.7–32.89
Untreated −8.29 m −19.10–2.52
<0.0001

Abbreviation: m, meters.