Table 5.

SMArtCARE Recommendations for Evaluation of SMA Patients

Baseline data including genetic test results

Current medical history and clinical examination o including motor milestones in children < 12 years of age

Physiotherapeutic assessments: CHOP INTEND o All children < 2 years of age o All patients > 2 years of age without ability to sit

HFMSE o All patients > 2 years of age with ability to sit o If CHOP INTEND score > 50: CHOP INTEND and HFMSE o If CHOP INTEND score > 60: HFMSE instead of CHOP INTEND

RULM o All patients > 2 years of age with ability to sit (in a wheelchair)

6MWT o All ambulant patients > 3 years of age

ALS Functional Rating Scale (in adult patients)

Pulmonary functiona

Documentation of adverse events

Note: ^aIf the patient is sufficiently cooperative due to age.