Weighted β-diversity of S rats and four congenic strains (RNO1, RNO5, RNO9, and RNO10) in both sexes. A: skin microbiota from S rats (female, n = 23; male, n = 22). B: oral microbiota from S rats (female, n = 24; male, n = 23). C: fecal microbiota from S rats (female, n = 24; male, n = 24). D: combined skin microbiota from rats (female, n = 23 S+32 congenic; male, n = 22 S+32 congenic). E: combined oral microbiota from rats (female, n = 24 S+31 congenic; male, n = 23 S+32 congenic). F: combined fecal microbiota from rats (female, n = 24 S+32 congenic; male, n = 24 S+32 congenic). ANOSIM P value was calculated using the QIIME II script, **P < 0.01. QIIME II, Quantitative Insights Into Microbial Ecology II; RNO, rat chromosomes; S, Dahl salt-sensitive.