Table 1.
The congenic strains and their blood pressure comparison in both males and females
Location of the Congenic Segment on the Rat Chromosomein Megabases | Congenic Strain | BP Effect in Females (Congenic minus S, mmHg) | BP Effect in Males (Congenic minus S, mmHg) |
---|---|---|---|
165,129,767-165,129,939 | RNO1 | −10* | −31*a |
116,151,550-120,258,073 & 122,679,504-133,413,079 | RNO5 | −7ns | −39*b |
25,819,185-99,041,068 | RNO9 | −21* | −27*c |
66,219,766-64,767,118 | RNO10 | −37* | −43*d |
*P < 0.05 as determined by unpaired t test; ns, not significant. aSaad et al. Physiological Genomics 2001 (16). bPillai et al. Physiological Genomics 2013 (17). cToland et al. Journal of Hypertension 2008 (18). dGarrett et al. Hypertension 2001 (19). BP, blood pressure; RNO, rat chromosomes; S, Dahl salt-sensitive.