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. 2022 May 3;54(7):231–241. doi: 10.1152/physiolgenomics.00167.2021

Table 1.

Statistical analysis results for blood pressure comparison between Btg2+/+ and Btg2−/− rats, within female and male

Two-Way ANOVA Female
Male
P Values WT vs. KO (WT vs. KO) vs. Time WT vs. KO (WT vs. KO) vs. Time
n n = 7, 8 n = 7, 8 n = 7, 6 n = 7, 6
24 h HR 0.015 ns ns ns
12 h day HR 0.001 ns ns ns
12 h night HR ns ns ns ns
norm (d-n) HR <0.0001 ns <0.0001 ns
24 h MAP <0.0001 ns ns ns
12 h day MAP <0.0001 ns ns ns
12 h night MAP <0.0001 ns ns ns
norm (d-n) MAP 0.003 0.005 0.004 ns
24 h SBP <0.0001 ns ns ns
12 h day SBP <0.0001 ns ns ns
12 h night SBP <0.0001 ns ns ns
norm (d-n) SBP ns 0.014 0.0006 ns
24 h DBP <0.0001 ns ns ns
12 h day DBP <0.0001 ns ns ns
12 h night DBP <0.0001 ns ns ns
norm (d-n) DBP <0.0001 0.011 0.004 ns
24 h PP 0.008 ns ns ns
12 h day PP 0.01 ns 0.002 ns
12 h night PP ns ns 0.001 ns
norm (d-n) PP <0.0001 ns ns ns

Values represent P value from two-way ANOVA for 6–8 rats/group. Within each sex the first column represents strain comparison, whereas the second column represents strain by time comparison. DBP, diastolic blood pressure; HR, heart rate; knockout (KO), Btg2−/−; MAP, mean arterial pressure; norm (d-n), (dark-light cycle)|/((dark + light cycle)/2); ns, not significant; PP, pulse pressure; SBP, systolic blood pressure; wild type (WT), Btg2+/+.