Table 1.
Two-Way ANOVA | Female |
Male |
||
---|---|---|---|---|
P Values | WT vs. KO | (WT vs. KO) vs. Time | WT vs. KO | (WT vs. KO) vs. Time |
n | n = 7, 8 | n = 7, 8 | n = 7, 6 | n = 7, 6 |
24 h HR | 0.015 | ns | ns | ns |
12 h day HR | 0.001 | ns | ns | ns |
12 h night HR | ns | ns | ns | ns |
norm (d-n) HR | <0.0001 | ns | <0.0001 | ns |
24 h MAP | <0.0001 | ns | ns | ns |
12 h day MAP | <0.0001 | ns | ns | ns |
12 h night MAP | <0.0001 | ns | ns | ns |
norm (d-n) MAP | 0.003 | 0.005 | 0.004 | ns |
24 h SBP | <0.0001 | ns | ns | ns |
12 h day SBP | <0.0001 | ns | ns | ns |
12 h night SBP | <0.0001 | ns | ns | ns |
norm (d-n) SBP | ns | 0.014 | 0.0006 | ns |
24 h DBP | <0.0001 | ns | ns | ns |
12 h day DBP | <0.0001 | ns | ns | ns |
12 h night DBP | <0.0001 | ns | ns | ns |
norm (d-n) DBP | <0.0001 | 0.011 | 0.004 | ns |
24 h PP | 0.008 | ns | ns | ns |
12 h day PP | 0.01 | ns | 0.002 | ns |
12 h night PP | ns | ns | 0.001 | ns |
norm (d-n) PP | <0.0001 | ns | ns | ns |
Values represent P value from two-way ANOVA for 6–8 rats/group. Within each sex the first column represents strain comparison, whereas the second column represents strain by time comparison. DBP, diastolic blood pressure; HR, heart rate; knockout (KO), Btg2−/−; MAP, mean arterial pressure; norm (d-n), (dark-light cycle)|/((dark + light cycle)/2); ns, not significant; PP, pulse pressure; SBP, systolic blood pressure; wild type (WT), Btg2+/+.