Table 2.

Renal measurements of female and male Btg2^+/+ and Btg2^−/− rats following high-salt diet

	Female		Male
	Btg2+/+	Btg2−/−	Btg2+/+	Btg2−/−
n	7	8	7	6
LS MAP, mmHg	120 ± 2	121 ± 1	122 ± 2	122 ± 4
HS19 MAP, mmHg	168 ± 4	186 ± 7*	181 ± 7	180 ± 6
UPro, mg/day	129 ± 16	238 ± 40*	509 ± 94	479 ± 99
UAlb, mg/day	98 ± 18	180 ± 33	328 ± 81	278 ± 68
UPro/UCr	16 ± 2	39 ± 12*	45 ± 12	38 ± 8
UAlb/UCr	12 ± 2	29 ± 9	31 ± 11	22 ± 5
UNa, mmol/L	372 ± 20	335 ± 20	284 ± 17	352 ± 60
UK, mmol/L	26 ± 2	26 ± 3	21 ± 2	28 ± 4
Body Wt, g	235 ± 6	210 ± 7*	327 ± 19	318 ± 17
Heart Wt, g	1.15 ± 0.03	1.10 ± 0.04	1.39 ± 0.05	1.36 ± 0.02
Kidney Wt, g	1.38 ± 0.05	1.30 ± 0.06	2.02 ± 0.08	1.91 ± 0.05
HW/BW, g/kg	4.9 ± 0.1	5.2 ± 0.2	4.3 ± 0.2	4.3 ± 0.2
KW/BW, g/kg	11.6 ± 0.2	12.6 ± 0.3*	12.8 ± 0.5	12.5 ± 0.7
Glom. Density	3.7 ± 0.2	3.3 ± 0.1*	2.6 ± 0.2	2.6 ± 0.2
Glom. Scl.	3.26 ± 0.05	2.70 ± 0.10*	3.09 ± 0.15	3.14 ± 0.15

Values represent means ± SE for 6–8 rats per group. *P < 0.05 between Btg2^−/− and Btg2^+/+ within sex, using an unpaired t test. BW, body weight; Glom. Scl, glomerular damage score; HS, high-salt diet; HS19, HS diet day 19; HW, heart weight; KW, kidney weight; LS, low-salt diet; MAP, mean arterial pressure; UAlb, urine albumin; UCr, urine creatinine; UK, urine potassium; UNa, urine sodium; UPro, urine protein.