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. 2022 Apr 29;13(4):10811–10826. doi: 10.1080/21655979.2022.2065789

Figure 4.

Figure 4.

Gene expression analysis of NASH-induced HepG2 spheroids post (72 h) treatment with Livogrit (0–30 µg/mL) and Pioglitazone (10 µM). MCDM-induced gene overexpression was observed in NASH associated genes: (a) FGF21, (b) FXR (c) CHOP, and (d) CXCL5 which decreased in the presence of Livogrit.