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. Author manuscript; available in PMC: 2022 Jun 20.
Published in final edited form as: Clin Sci (Lond). 2020 Dec 23;134(24):3237–3257. doi: 10.1042/CS20201023

Figure 6. Distribution of the lymphatic vasculature in the adult ovary of Prox1-EGFP reporter mice.

Figure 6.

The adult ovary possesses a rich lymphatic network largely overlapping with the blood vasculature. (A) Prox 1-EGFP-positive lymphatics were observed throughout the ovary, originating from the rete ovarii (RO) (arrow), and extending into the ovarian medulla (Om) and ovarian cortex (Oc). (B) Endoglin (ENG) labeling showed an extensive network of blood vessels in the ovary with the follicle (F) indicated by an arrow. (C) Lyve-1 positive lymphatic vessels were confined to the ovarian and extraovarian rete. (D) A 3-D representative image showing Prox1-EGFP-positive lymphatics. (E) Lyve1- positive lymphatic vessels and ENG-positive blood vessels. (F) Combined image showed some colocalization of Prox1, Lyve1, and ENG and a distinct pattern of the blood and lymphatic network in the adult ovary; scale bar = 1 mm. The images are reproduced from the reference [119] with permission.