Table 2.
Association of glucose and glucose-corrected plasma sodium fluctuations with neonatal characteristics and complications, without and with adjustment for gestational age.
| Glucose | Glucose (adj. for GA) | Glucose-corrected plasma sodium | Glucose-corrected plasma sodium (adj. for GA) | |
|---|---|---|---|---|
| Gestational age |
−0.95* (−1.29, −0.61) |
— |
−1.40* (−1.95, −0.86) |
— |
| Male sex |
0.03 (−1.17, 1.24) |
0.31 (−0.8, 1.41) |
0.53 (−1.37, 2.43) |
0.94 (−0.82, 2.70) |
| SNAP score |
0.03 (−0.03, 0.09) |
−0.01 (−0.07, 0.05) |
0.10* (0.00, 0.19) |
0.06 (−0.03, 0.15) |
| Severe IVH |
2.69 (−0.09, 5.48) |
0.53 (−2.15, 3.22) |
7.22* (2.94, 11.51) |
4.46* (0.20, 8.72) |
| NSAID-treated PDA |
0.84 (−0.48, 2.16) |
−0.88 (−2.27, 0.5) |
4.89* (3.01, 6.76) |
3.84* (1.72, 5.96) |
| Acute kidney injury |
4.88* (3.23, 6.53) |
3.86* (2.24, 5.49) |
2.93* (0.09, 5.77) |
1.05 (−1.73, 3.82) |
| Death at 36 weeks’ GA or moderate-to-severe BPD |
2.25* (0.99, 3.52) |
1.08 (−0.22, 2.38) |
3.68* (1.69, 5.66) |
2.02 (−0.05, 4.09) |
Sodium and glucose fluctuations were defined by the difference between the maximal value and the minimal value recorded for each individual within the time period. Results are shown as coefficients B with 95% confidence interval (CI) calculated using linear regression.
ROP retinopathy of prematurity, severe IVH intraventricular hemorrhage grade 3 or 4, adj. for GA adjusted for gestational age.
*p < 0.05.