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Metastatic but not primary melanoma tumor cells respond to IFN-λ. Paired primary and metastatic melanoma tumor cell lines from 3 patients were stimulated with IFN-α, IFN-λ, or IFN-γ for 20 min. IFN-λ responsiveness was measured by immunoblot analysis of phosphotyrosine-701 STAT1. IFN, interferon.
