3.2. Analysis.
Comparison 3 Faecal incontinence: crossover trials, Outcome 2 Episodes of faecal incontinence per week.
Episodes of faecal incontinence per week | ||||||||||
---|---|---|---|---|---|---|---|---|---|---|
Study | Group | Measure | Patients | Baseline | Three months | 'Off' period | 'On' period | Change (%) | Follow‐up | Notes |
Kahlke 2015# | Mean (SD) | 14 | 18 (19.6) | 8.4 (8.7) | 1 (1.7) | ‐7.4 ( ‐ 88%) | 0.3 (0.5) | p<0.05 | ||
Kahlke 2015# | ||||||||||
Leroi 2005# | Group of 19 who chose 'on' following the crossover period | Median (range) | Baseline: 16 3 months: 16 'Off' period: 19 'On' period: 19 Follow‐up: 18 | 3.5 (0 to 16) | 0.3 (0 to 3) | 1.7 (0 to 9) | 0.7 (0 to 5) | ‐1 (‐59%) | 0.5 (0 to 11) | 1. P < 0.05: 'off' versus 'on' period; 3 months, 'off' period, 'on' period, follow‐up period versus baseline. |
Leroi 2005# | Group of 5 who chose 'off' following the crossover period | Median (range) | Baseline: 5 3 months: 4 'Off' period: 5 'On' period: 5 Follow‐up: 5 | 7 (0 to 11) | 1.9 (1 to 10) | 1.7 (0 to 11) | 3.7 (0 to 11) | 2 (118%) | 3.5 (0 to 10) | |
Sørensen 2010# | Mean | 7 | 0 | 0 | 0 | |||||
Sørensen 2010# | ||||||||||
Thin 2015 | PTNS group | Mean±SD | 16 | 10.6 ± 11.2 | 5.8 ± 6.9 | ‐4.3 (‐41%) | 6.3 ± 6.9 | Follow up was at 6 months. % change is reported as the difference between baseline and at 6 months. | ||
Thin 2015 | SNS group | Mean±SD | 15 | 12.1 ± 13.7 | 2.8 ± 2.5 | ‐9 (‐74%) | 3.1 ± 4.0 | Follow up was at 6 months. % change is reported as the difference between baseline and at 6 months. | ||
Tjandra 2008 | Control group | Mean±SD | 60 | 9.2±13.4 | 8.1±14.1 | 0.2 (2%) | 9.4±11.8 | P > 0.05 at 3 months and 12 months compared with baseline. Follow‐up was at 12 months. % change is reported as the difference between baseline and at 12 months. | ||
Tjandra 2008 | SNS group | Mean±SD | 53 | 9.5±12.8 | 2.9±6.3 | ‐6.4 (‐67%) | 3.1±10.1 | P < 0.0001 at all time points compared with baseline. Follow‐up was at 12 months. % change is reported as the difference between baseline and at 12 months. | ||
Vaizey 2000# | Mean (range) | 2 | 10 (5 and 15) | 6 (2 and 10) | 1 (0 and 1) | ‐5 (‐83%) | ||||
Vaizey 2000# |