Days with staining per week
Study	Group	Measure	Patients	Baseline	Three months	12 months	Change (%)	Notes
Tjandra 2008	Control group	Mean±SD	60	4.3±1.9	4.5±2.1	4.5±2.3	0.2 (5%)	P > 0.05 at 3 months and 12 months compared with baseline. % change is reported as the difference between baseline and at 12 months.
Tjandra 2008	SNS group	Mean±SD	53	4±2.3	1.3±1.7	1.4±2	‐2.6 (‐65%)	P < 0.0001 at all time points compared with baseline. % change is reported as the difference between baseline and at 12 months.