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. 2022 May 13;6(6):e722. doi: 10.1097/HS9.0000000000000722

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Copyright © 2022 the Author(s). Published by Wolters Kluwer Health, Inc. on behalf of the European Hematology Association.

This is an open access article distributed under the Creative Commons Attribution License 4.0 (CCBY), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 1. — Increased expression of glycolytic and mitochondrial markers within proliferation centers in CLL lymph nodes. The expression of GLUT3 (A), HK2 (B), NDUFS3 (C), and TOMM20 (D) was assessed in lymph node CLL cells by immunohistochemistry. Representative images of whole cores are shown. Detailed images show higher expression of Ki67 (A, B, C, D), GLUT3 (A), HK2 (B), NDUFS3 (C), and TOMM20 (D) in CLL cells within proliferation centers (arrowed). n = 26 for GLUT3 and HK2, n = 15 for NDUFS3 and TOMM20. CLL = chronic lymphocytic leukemia.