Table 2.
GU, n = 511 | PSU, n = 163 | p value | |
---|---|---|---|
Drugs, median (IQR) | 7 (5) | 7 (4) | 0.580 |
Psychotropic drugs, median (IQR) | 1 (1) | 2 (1) | < 0.001* |
No psychotropic drugs | 114 (22.3) | 9 (5.5) | |
1 treatment group | 165 (32.3) | 30 (18.4) | |
2 treatment groups | 147 (28.8) | 62 (38.0) | |
≥ 3 treatment groups | 85 (16.6) | 62 (38.0) | |
Antipsychotics | 159 (31.1) | 128 (78.5) | < 0.001* |
Quetiapine | 83 (52.2) | 76 (59.4) | 0.224 |
Risperidone | 39 (24.5) | 37 (28.9) | 0.403 |
Olanzapine | 11 (6.9) | 16 (12.5) | 0.107 |
Clozapine | 6 (3.8) | 5 (3.9) | 0.954 |
Aripiprazole | 9 (5.7) | 1 (0.8) | 0.047* |
Equivalent risperidone, median (IQR) | 1(2) | 1.5 (3) | 0.040 |
Equivalent risperidone >2 mg | 48 (30.2) | 51 (39.8) | 0.100 |
Benzodiazepines | 170 (33.3) | 47 (28.8) | 0.291 |
Lorazepam | 96 (56.5) | 25 (53.2) | 0.689 |
Lormetazepam | 38 (22.4) | 11 (23.4) | 0.879 |
Diazepam | 12 (7.1) | 4 (8.5) | 0.736 |
Alprazolam | 12 (7.1) | 2 (4.3) | 0.739 |
Bromazepam | 8 (4.7) | 0 (0.0) | 0.206 |
Clorazepate | 4 (2.4) | 3 (6.4) | 0.175 |
Equivalent lorazepam, median (IQR) | 1 (1) | 1 (1) | 0.164 |
Antidepressants | 281 (55.0) | 114 (69.9) | < 0.001* |
Trazodone | 121 (43.1) | 55 (48.2) | 0.347 |
SSRIs | 113 (40.2) | 46 (40.4) | 0.980 |
Mirtazapine | 75 (26.7) | 27 (23.7) | 0.536 |
SNRIs | 51 (18.1) | 12 (10.5) | 0.061 |
Vortioxetine | 10 (3.6) | 2 (1.8) | 0.344 |
Antiepileptic drugs | 110 (21.5) | 60 (36.8) | < 0.001* |
Pregabaline | 47 (44.3) | 31 (54.4) | 0.252 |
Levetiracetam | 25 (23.6) | 6 (10.5) | 0.043* |
Valproic acid | 11 (10.4) | 8 (14.0) | 0.488 |
Gabapentine | 2 (1.9) | 7 (12.3) | 0.009* |
Topiramate | 4 (3.8) | 4 (7.0) | 0.452 |
Data are presented as n (%) unless otherwise stated
GU geriatric units, IQR interquartile range, PSU psychogeriatric units, SNRIs serotonin-norepinephrine reuptake inhibitor, SSRI selective serotonin reuptake inhibitors, *p < 0.05