| Author (year) | No. of participants | Participant experiencing adverse events* % (n) | ||
| Any severity | Serious adverse event | Related to drug | ||
| Bui 2020 | 155 | 0.0 (0) | ‐ | ‐ |
| Han 2020 | 390 | 0.0 (0) | ‐ | ‐ |
| Leang 2016 | 117 | 91.1 (112) | 0.0 (0) | ‐ |
| Leang 2019a | 224 | 100.0 (120) | 0.0 (0) | ‐ |
| Leang 2019b | 121 | 87.6 (106) | 0.0 (0) | ‐ |
| Lutete 2021a | 7746 | 20.8 (1490) | 0.4 (29) | 9.6 (685) |
| Ramharter 2008 | 59 | 83.0 (49) | 3.4 (2) | 28.8 (17) |
| *Includes adverse events reported at baseline in some studies. | ||||
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