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. 2022 Jun 20;8:77. doi: 10.1038/s41531-022-00343-6

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© The Author(s) 2022

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 1 — The average PSD spectra of 29 and 20 continuous 5-min LFP recordings from 10 control (blue) and 11 parkinsonian (6-OHDA, red) rats, respectively. The open field test (OFT) reveals a significantly higher peak in the α band (7–10 Hz) in control than in parkinsonian rats in both MC (a) and STN (b). Meanwhile, there is a lower δ band (1–4 Hz) power in both MC and STN in control than in parkinsonian rats, although the differences are statistically insignificant. In contrast, a peak oscillation in β band (20–40 Hz) in parkinsonian but not in control rats is noted only in MC. PSD spectra were presented as mean (solid curves) ± standard deviation (shaded areas). Data in the bar plots were presented as mean ± standard error of mean (S.E.M.). Data were analyzed with Mann–Whitney U tests. **p < 0.01, N.S., nonsignificant.