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. 2022 Jun 20;13:3535. doi: 10.1038/s41467-022-31124-7

Fig. 9. High EPHB4-low EFNB2 correlates with better overall and disease-free survival in HNSCC patients.

Fig. 9

TCGA database was interrogated and a overall survival (OS) and b progression-free interval (PFI) was calculated in HNSCC patients expressing high and low levels of EPHB4 by Kaplan–Meir method using log-rank test for comparison. The number of patients analyzed is mentioned in the respective figures. Data represented in c and d corresponds to better overall survival and progression-free interval (PFI) in patients with high EPHB4-low EFNB2 compared to low EPHB4-high EFNB2 cohort. e Multivariate cox analysis for OS and DFS was performed on TCGA HNSCC patients with high EPHB4-low EFNB2 controlling for age, gender, disease site, alcohol consumption, smoking, and tumor size (T), and lymph node status. HR, hazard ratio, CI, confidence interval.