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. 2022 Jun 20;12:10391. doi: 10.1038/s41598-022-14213-x

Table 3.

Summary of findings table of stretching exercise intervention for fibromyalgia symptoms in adults.

Oucome Anticipated absolute effects* (95% CI) No. of participants (studies) Certainty of the evidence (GRADE) Information statements
Pain

SMD 1.05 SD lower

(1.79 lower to 0.3 lower)

225 (5 RCTs)

⨁◯◯◯a,b,c,d

Very low

ST may decrease pain symptoms in adults with FM
Depression

SMD 0.85 SD lower

(2.13 lower to 0.43 higher)

119 (2 RCTs)

⨁◯◯◯a,b,c,d

Very low

ST may decrease depression symptoms in adults with FM
FIQ

SMD 0.92 SD lower

(1.3 lower to 0.56 lower)

123 (2 RCTs)

⨁◯◯◯a,c,d

Very low

ST may decrease the impact of the FM on quality of life
Mental component HRQOL

SMD 0.42 SD higher

(0.06 higher to 0.79 higher)

120 (2 RCTs)

⨁◯◯◯a,c,d,e

Very low

ST increase Mental Component HRQOL symptoms in adults with FM
Physical component HRQOL

SMD 1.05 SD higher

(0.66 higher to 1.43 higher)

120 (2 RCTs)

⨁◯◯◯a,c,d,e

Very low

ST increase Physical Component HRQOL symptoms in adults with FM

Significant values are in bold.

*The risk in the intervention group (and its 95% confidence interval) is based on the assumed risk in the comparison group and the relative effect of the intervention (and its 95% interval confidence).

aLarge number of studies with high risk of bias.

bHeterogeneity present and significant.

cDifferences in interventions and outcomes measures.

dN is under 300.

eAsymmetry in the pattern of results.