Table 1.
Demographics and Baseline Characteristics of Subjects
| Macula Cohort (n = 42, 49 Eyes) | ONH cohort (n = 60, 73 Eyes) | Combined Cohort (n = 68, 88 Eyes) | |
|---|---|---|---|
|
| |||
| Age (years) | 66.6 (62.6, 70.6) | 68.8 (65.7, 71.9) | 68.8 (65.9, 71.6) |
| Gender (M/F) | 15/27 | 23/37 | 25/43 |
| Race | |||
| African Descents (%) | 11 (26.2%) | 16 (26.7%) | 19 (27.9%) |
| European Descents (%) | 24 (57.1%) | 37 (61.7%) | 39 (57.4%) |
| Others (%) | 7 (16.7%) | 7 (11.7%) | 10 (14.7%) |
| Axial Length (mm) | 24 (23.8, 24.3) | 24.0 (23.8, 24.3) | 24.0 (23.8, 24.2) |
| CCT (μm) | 539.4 (529.9, 548.8) | 539.6 (530.1, 549.1) | 537.1 (528.6, 545.6) |
| Spherical Equivalent (D) | −0.95 (−1.41, −0.49) | −0.73 (−1.13, −0.32) | −0.79 (−1.15, −0.43) |
| Baseline IOP (mmHg) | 15.0 (13.8, 16.2) | 14.7 (13.5, 15.8) | 15.1 (14.0, 16.1) |
| Diagnosis by subject | |||
| Healthy, n (%) | 9 (18.4%) | 13 (17.8%) | 15 (17.0%) |
| Glaucoma suspect, n (%) | 23 (46.9%) | 30 (41.1%) | 38 (43.2%) |
| Glaucoma, n (%) | 17 (34.7%) | 30 (41.1%) | 35 (39.8%) |
| Baseline 24-2 MD (dB) | −0.47 (−0.85, −0.08) | −0.85 (−1.25, −0.45) | −0.82 (−1.17, −0.46) |
| Average SSI | 70.1 (68.1, 72.1) | 64.2 (62.4, 66.1) | |
| Average wiVD (%) | 44.8 (43.7, 46.0) | ||
| Average pfVD (%) | 47.8 (47.0, 48.9) | ||
| Average wiGCC (μm) | 97.0 (93.7, 100.1) | ||
| Average pfGCC (μm) | 102.3 (98.9, 105.6) | ||
| Average wiCD (%) | 44.7 (43.7, 45.6) | ||
| Average cpCD (%) | 46.5 (45.4, 47.5) | ||
| Average cpRNFL (μm) | 90.8 (87.2, 94.3) | ||
| Follow-up for OCTA (years) | 1.2 (1.2, 1.2) | 1.2 (1.2, 1.2) | |
| Visits | 3.1 (3.0, 3.2) | 3.0 (3.0, 3.1) | |
| Visual field follow-up period for glaucoma patients | 8.7 (6.0, 11.5) | 10.1 (8.5, 11.7) | |
| Visual field follow-up period for glaucoma suspect subject | 9.7 (7.2, 12.3) | 9.6 (7.1, 12.0) | |
CCT = central corneal thickness; CD = capillary density; cp = circumpapillary; D = diopter; F = female; GCC = ganglion cell complex; IOP = intraocular pressure; ONH = optic nerve head; pf = parafoveal; RNFL = retinal nerve fiber layer; SSI = signal strength index; VD = vessel density; wi = whole image; M = male; MD = mean deviation. Values are shown in mean (95% confident interval), unless otherwise indicated.