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. Author manuscript; available in PMC: 2023 May 1.
Published in final edited form as: Br J Ophthalmol. 2021 Dec 21;107(5):657–662. doi: 10.1136/bjophthalmol-2021-320034

Table 4.

Effect of age, SSI, 24-2 VF MD, and IOP on the variability of OCTA and OCT measurements for ONH parameters

Coefficient, 95% CI R-squared, 95% CI p value

wiCD
 Age −0.14 (−0.22, −0.06) 0.29 (0.20, 0.39) 0.001
 SSI 0.58 (0.23, 0.94) 0.05 (0.01, 0.12) 0.002
 24-2 VF MD 0.65 (0.11, 1.19) 0.17 (0.09, 0.26) 0.022
 IOP −0.08 (−0.27, 0.10) 0.03 (0.00, 0.09) 0.386
cpCD
 Age −0.15 (−0.24, −0.06) 0.29 (0.20, 0.39) 0.002
 SSI 0.23 (−0.16, 0.61) 0.01 (0.00, 0.05) 0.247
 24-2 VF MD 0.62 (0.02, 1.21) 0.14 (0.06, 0.23) 0.045
 IOP −0.12 (−0.32, 0.08) 0.05 (0.01, 0.12) 0.237
cpRNFL
 Age −0.43 (−0.75, −0.11) 0.49 (0.40, 0.57) 0.011
 SSI 0.26 (−0.31, 0.83) 0.00 (0.00, 0.03) 0.374
 24-2 VF MD 1.08 (−0.89, 3.04) 0.12 (0.05, 0.20) 0.287
 IOP 0.01 (−0.64, 0.65) 0.00 (0.00, 0.02) 0.984

CD = capillary density; CI = confidence interval; cp = circumpapillary; IOP = intraocular pressure; MD = mean deviation; OCT = optical coherence tomography; OCTA = optical coherence tomography angiography; ONH = optic nerve head; RNFL = retinal nerve fiber layer; SSI = signal strength index; VD = vessel density; VF = visual field; wi = whole image. Values are shown in β coefficient (95% confident interval). Negative coefficient demonstrates that reproducibility decreased with increasing the values of the putative factor. Statistically significant p value is shown in bold.