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. 2022 Apr 30;12(6):1313–1323. doi: 10.1007/s13555-022-00733-x

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© The Author(s) 2022

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Fig. 2 — Fluorescence imaging of dermal biomarker patches. DBP were chemically modified adjacent to the microneedles with T24 oligonucleotides and then CY3-A24 hybridized for imaging. Strong fluorescence between the modified and unmodified regions can be seen and was quantified using ImageJ. A Fluorescence imaging of the DBP; B fluorescence imaging of spot on the DBP backplate used for quantitative assessment of chemical modification